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1

Induction of Proliferative Lesions of the Uterus, Testes, and Liver in Swiss Mice Given Repeated Injections of Sodium Arsenate: Possible Estrogenic Mode of Action

Michael P. Waalkes, Larry K. Keefer, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2000

Language:

english

File:

PDF, 1.02 MB

english, 2000

2

Arsenic-induced malignant transformation of human keratinocytes: Involvement of Nrf2

Jingbo Pi, Bhalchandra A. Diwan, Yang Sun, Jie Liu, Wei Qu, Yuying He, Miroslav Styblo, Michael P. Waalkes

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 985 KB

english, 2008

3

DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis

Vassilis L Souliotis, John R Henneman, Carl D Reed, Saranjit K Chhabra, Bhalchandra A Diwan, Lucy M Anderson, Soterios A Kyrtopoulos

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2002

Language:

english

File:

PDF, 185 KB

english, 2002

4

K-ras mutations in mouse lung tumors of extreme age: independent of paternal preconceptional exposure to chromium(III) but significantly more frequent in carcinomas than adenomas

Ilda M McKenna, Gayatri Ramakrishna, Bhalchandra A Diwan, Yih-Horng Shiao, Kazimierz S Kasprzak, Douglas A Powell, Lucy M Anderson

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2001

Language:

english

File:

PDF, 279 KB

english, 2001

5

Arsenic Exposure Transforms Human Epithelial Stem/Progenitor Cells into a Cancer Stem-like Phenotype

Erik J. Tokar, Bhalchandra A. Diwan and Michael P. Waalkes

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

6

Polymerase chain reaction–single-strand conformation polymorphism analysis for the VHL gene in chemically induced kidney tumors of rats using intron-derived primers

Yih-Horng Shiao, Bhalchandra A. Diwan, Alan O. Perantoni, Richard J. Calvert, Berton Zbar, Michael I. Lerman, Jerry M. Rice

Journal:

Molecular Carcinogenesis

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

7

Deficient expression of mRNA for the putative inductive factor bone morphogenetic protein-7 in chemically initiated rat nephroblastomas

Kathleen G. Higinbotham, Irina D. Karavanova, Bhalchandra A. Diwan, Alan O. Perantoni

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 606 KB

english, 1998

8

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3′-azido-2′,3′-dideoxythymidine

Zhihua Zhang, Bhalchandra A. Diwan, Lucy M. Anderson, Daniel Logsdon, Ofelia A. Olivero, Diana C. Haines, Jerry M. Rice, Stuart H. Yuspa, Miriam C. Poirier

Journal:

Molecular Carcinogenesis

Year:

1998

Language:

english

File:

PDF, 103 KB

english, 1998

9

Ki-ras and the Characteristics of Mouse Lung Tumors

Gayatri Ramakrishna, Aneta Bialkowska, Christine Perella, Lisa Birely, Laura W. Fornwald, Bhalchandra A. Diwan, Yih-Horng Shiao, Lucy M. Anderson

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 707 KB

english, 2000

10

Enhanced tumorigenesis and reduced transforming growth factor-β type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-β1

Yang Kang, Jennifer M. Mariano, Jerry Angdisen, Terry W. Moody, Bhalchandra A. Diwan, Lalage M. Wakefield, Sonia B. Jakowlew

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 306 KB

english, 2000

11

Cadmium-induced malignant transformation in rat liver cells: Role of aberrant oncogene expression and minimal role of oxidative stress

Wei Qu, Bhalchandra A. Diwan, Jeffrey M. Reece, Carl D. Bortner, Jingbo Pi, Jie Liu, Michael P. Waalkes

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 549 KB

english, 2005

12

Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: Potential role in skin co-carcinogenesis

Jingbo Pi, Yuying He, Carl Bortner, Jianli Huang, Jie Liu, Tong Zhou, Wei Qu, Susan L. North, Kazimierz S. Kasprzak, Bhalchandra A. Diwan, Colin F. Chignell, Michael P. Waalkes

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

13

Hypersusceptibility to cisplatin carcinogenicity in metallothionein-I/II double knockout mice: Production of hepatocellular carcinoma at clinically relevant doses

Michael P. Waalkes, Jie Liu, Kazimierz S. Kasprzak, Bhalchandra A. Diwan

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

14

Hepatic cytochrome P450 2B induction by ethyl/ phenyl-substituted congeners of phenobarbital in the B6C3F1 mouse

Dr. Raymond W. Nims, Ronald A. Lubet, Bhalchandra A. Diwan, Donna W. Mellini, William E. Utermahlen Jr., Paul E. Thomas

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1994

Language:

english

File:

PDF, 930 KB

english, 1994

15

Iron accelerates while magnesium inhibits nickel-induced carcinogenesis in the rat kidney

Kazimierz S. Kasprzak, Bhalchandra A. Diwan, Jerry M. Rice

Journal:

Year:

1994

Language:

english

File:

PDF, 1.56 MB

english, 1994

16

Relative susceptibilities of C57BL6, (C57BL6 × C3HHe)F1, and C3HHe mice to acute toxicity and carcinogenicity of nickel subsulfide

Ricardo E. Rodriguez, Manoj Misra, Bhalchandra A. Diwan, Charles W. Riggs, Kazimierz S. Kasprzak

Journal:

Year:

1996

Language:

english

File:

PDF, 854 KB

english, 1996

17

Mechanisms underlying arsenic carcinogenesis: hypersensitivity of mice exposed to inorganic arsenic during gestation

Michael P Waalkes, Jie Liu, Jerrold M Ward, Bhalchandra A Diwan

Journal:

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

18

Arsenicals in maternal and fetal mouse tissues after gestational exposure to arsenite

Vicenta Devesa, Blakely M. Adair, Jie Liu, Michael P. Waalkes, Bhalchandra A. Diwan, Miroslav Styblo, David J. Thomas

Journal:

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

19

Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H mice

Gene J. Ahlborn, Gail M. Nelson, Rachel D. Grindstaff, Michael P. Waalkes, Bhalchandra A. Diwan, James W. Allen, Kirk T. Kitchin, R. Julian Preston, Araceli Hernandez-Zavala, Blakely Adair, David J. T

Journal:

Year:

2009

Language:

english

File:

PDF, 904 KB

english, 2009

20

Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic

Gail M. Nelson, Gene J. Ahlborn, James W. Allen, Hongzu Ren, J. Christopher Corton, Michael P. Waalkes, Kirk T. Kitchin, Bhalchandra A. Diwan, Geremy Knapp, Don A. Delker

Journal:

Year:

2009

Language:

english

File:

PDF, 1.17 MB

english, 2009

21

Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid onN-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat

Bhalchandra A. Diwan, Raymond W. Nims, John R. Henneman, Jerrold M. Ward, Ronald A. Lubet, Jerry M. Rice

Journal:

Archives of Toxicology

Year:

1992

Language:

english

File:

PDF, 2.25 MB

english, 1992

22

neumutation in schwannomas induced transplacentally in Syrian golden hamsters byN-nitrosoethylurea: high incidence but low allelic representation

Gregory S. Buzard, Takayuki Enomoto, Tadashi Hongyo, Alan O. Perantoni, Bhalchandra A. Diwan, Deborah E. Devor, Carl D. Reed, Lee F. Dove, Jerry M. Rice

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1999

Language:

english

File:

PDF, 307 KB

english, 1999

23

Aberrant DNA methylation and gene expression in livers of newborn mice transplacentally exposed to a hepatocarcinogenic dose of inorganic arsenic

Yaxiong Xie, Jie Liu, Lamia Benbrahim-Tallaa, Jerry M. Ward, Daniel Logsdon, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

24

Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice

Erik J. Tokar, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Year:

2010

Language:

english

File:

PDF, 474 KB

english, 2010

25

Micro-MRI methods to detect renal cysts in mice

Kobayashi, Hisataka, Kawamoto, Satomi, Brechbiel, Martin W., Jo, Sang-Kyung, Hu, Xuzhen, Yang, Tianxin, Diwan, Bhalchandra A., Waldmann, Thomas A., Schnermann, Jurgen, Choyke, Peter L., Star, Robert A

Journal:

Kidney International

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

26

Selective mutation of K-ras by N-ethylnitrosourea shifts from codon 12 to codon 61 during fetal mouse lung maturation

Sithanandam, Gunamani, Ramakrishna, Gayatri, Diwan, Bhalchandra A, Anderson, Lucy M

Journal:

Year:

1998

Language:

english

File:

PDF, 459 KB

english, 1998

27

Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas

Renata Kowara, Konstantin Salnikow, Bhalchandra A. Diwan, Robert M. Bare, Michael P. Waalkes, Kazimierz S. Kasprzak

Journal:

Molecular and Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 121 KB

english, 2004

28

The inheritance of susceptibility and resistance to the teratogenic effect of 1-ethyl-1-nitrosourea in Inbred Strains of mice

Bhalchandra A. Diwan, Hans Meier

Journal:

Birth Defects Research Part A: Clinical and Molecular Teratology

Year:

1974

Language:

english

File:

PDF, 337 KB

english, 1974

29

Microsatellite Instability Is Infrequent in Azoxymethane-Induced Rat Intestinal Tumors: An Assessment by Capillary Electrophoresis

Cynthia Walchle, Bhalchandra A. Diwan, Yih-Horng Shiao, Richard J. Calvert

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 75 KB

english, 1999

30

Preconception Urethane or Chromium(III) Treatment of Male Mice: Multiple Neoplastic and Non-neoplastic Changes in Offspring

Wei Yu, Marek A. Sipowicz, Diana C. Haines, Lisa Birely, Bhalchandra A. Diwan, Charles W. Riggs, Kazimierz S. Kasprzak, Lucy M. Anderson

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 122 KB

english, 1999

31

Multiorgan Transplacental and Neonatal Carcinogenicity of 3′-Azido-3′-deoxythymidine in Mice

Bhalchandra A. Diwan, Charles W. Riggs, Daniel Logsdon, Diana C. Haines, Ofelia A. Olivero, Jerry M. Rice, Stuart H. Yuspa, Miriam C. Poirier, Lucy M. Anderson

Journal:

Toxicology and Applied Pharmacology

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

32

Association of c-myc Overexpression and Hyperproliferation with Arsenite-Induced Malignant Transformation

Hua Chen, Jie Liu, Christopher Q. Zhao, Bhalchandra A. Diwan, Bruce A. Merrick, Michael P. Waalkes

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 139 KB

english, 2001

33

Decrease in K-ras p21 and Increase in Raf1 and Activated Erk 1 and 2 in Murine Lung Tumors Initiated by N-Nitrosodimethylamine and Promoted by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

Gayatri Ramakrishna, Christine Perella, Lisa Birely, Bhalchandra A. Diwan, Laura W. Fornwald, Lucy M. Anderson

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 543 KB

english, 2002

34

Age- and dose-dependent transplacental carcinogenesis byN-nitrosoethylurea in Syrian golden hamsters

Bhalchandra A. Diwan, Sabine Rehm, Jerry M. Rice

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

1996

Language:

english

File:

PDF, 2.27 MB

english, 1996

35

Tumors and proliferative lesions in adult offspring after maternal exposure to methylarsonous acid during gestation in CD1 mice

Erik J. Tokar, Bhalchandra A. Diwan, David J. Thomas, Michael P. Waalkes

Journal:

Archives of Toxicology

Year:

2012

Language:

english

File:

PDF, 320 KB

english, 2012

36

Lack of effect of phenobarbital on hepatocellular carcinogenesis initiated by N-nitrosodiethylamine or methylazoxymethanol acetate in male Syrian golden hamsters

Bhalchandra A. Diwan, Jerrold M. Ward, Lucy M. Anderson, Akihiro Hagiwara, Jerry M. Rice

Journal:

Toxicology and Applied Pharmacology

Year:

1986

Language:

english

File:

PDF, 3.53 MB

english, 1986

37

The chronic hepatic or renal toxicity of di(2-ethylhexyl) phthalate, acetaminophen, sodium barbital, and phenobarbital in male B6C3F1 mice: Autoradiographic, immunohistochemical, and biochemical evidence for levels of DNA synthesis not associated with carcinogenesis or tumor promotion

Jerrold M. Ward, Akihiro Hagiwara, Lucy M. Anderson, Kimberly Lindsey, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

1988

Language:

english

File:

PDF, 3.47 MB

english, 1988

38

Effects of sodium salts of phenobarbital and barbital on development of bladder tumors in male F344>NCr rats pretreated with either N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-nitrosobutyl-4-hydroxybutylamine

Bhalchandra A. Diwan, Akihiro Hagiwara, Jerrold M. Ward, Jerry M. Rice

Journal:

Toxicology and Applied Pharmacology

Year:

1989

Language:

english

File:

PDF, 713 KB

english, 1989

39

Correlation of DNA base oxidation with the activation of K-ras oncogene in nickel-induced renal tumors

Kazimierz S. Kasprzak, Kathleen Higinbotham, Bhalchandra A. Diwan, Alan O. Perantoni, Jerry M. Rice

Journal:

Free Radical Biology and Medicine

Year:

1990

Language:

english

File:

PDF, 106 KB

english, 1990

40

Fetal arsenic exposure appears to facilitate endocrine disruption by postnatal diethylstilbestrol in neonatal mouse adrenal

Jie Liu, Limei Yu, Jean-Francois Coppin, Erik J. Tokar, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 514 KB

english, 2009

41

Animal models for arsenic carcinogenesis: inorganic arsenic is a transplacental carcinogen in mice

Michael P Waalkes, Jie Liu, Jerrold M Ward, Bhalchandra A Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2004

Language:

english

File:

PDF, 438 KB

english, 2004

42

Transplacental arsenic plus postnatal 12-O-teradecanoyl phorbol-13-acetate exposures associated with hepatocarcinogenesis induce similar aberrant gene expression patterns in male and female mouse liver

Jie Liu, Yaxiong Xie, B. Alex Merrick, Jun Shen, Danica M.K. Ducharme, Jennifer Collins, Bhalchandra A. Diwan, Daniel Logsdon, Michael P. Waalkes

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 521 KB

english, 2006

43

Enhanced urinary bladder and liver carcinogenesis in male CD1 mice exposed to transplacental inorganic arsenic and postnatal diethylstilbestrol or tamoxifen

Michael P. Waalkes, Jie Liu, Jerrold M. Ward, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2006

Language:

english

File:

PDF, 478 KB

english, 2006

44

Transplacental exposure to inorganic arsenic at a hepatocarcinogenic dose induces fetal gene expression changes in mice indicative of aberrant estrogen signaling and disrupted steroid metabolism

Jie Liu, Yaxiong Xie, Ryan Cooper, Danica M.K. Ducharme, Raymond Tennant, Bhalchandra A. Diwan, Michael P. Waalkes

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 466 KB

english, 2007

45

Transplacental arsenic carcinogenesis in mice

Michael P. Waalkes, Jie Liu, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2007

Language:

english

File:

PDF, 483 KB

english, 2007

46

Metallothionein protection of cadmium toxicity

Curtis D. Klaassen, Jie Liu, Bhalchandra A. Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2009

Language:

english

File:

PDF, 376 KB

english, 2009

47

Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice

Kazimierz S. Kasprzak, Bhalchandra A. Diwan, Monika Z. Kaczmarek, Daniel L. Logsdon, Mathew J. Fivash, Konstantin Salnikow

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 352 KB

english, 2011

48

Alterations in membrane-bound and cytoplasmic K-ras protein levels in mouse lung induced by treatment with lovastatin, cholestyramine, or niacin: effects are highly mouse strain dependent

Richard J Calvert, Gayatri Ramakrishna, Shirley Tepper, Bhalchandra A Diwan, Lucy M Anderson, David Kritchevsky

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 353 KB

english, 2002

49

Treatment with lovastatin, cholestyramine or niacin alters K-ras membrane association in mouse lung in a strain-dependent manner: results in females

Richard J Calvert, Shirley Tepper, Bhalchandra A Diwan, Lucy M Anderson, David Kritchevsky

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 367 KB

english, 2003

50

Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice

Michael P Waalkes, Jerrold M Ward, Jie Liu, Bhalchandra A Diwan

Journal:

Toxicology and Applied Pharmacology

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003